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Ethyl Butylacetylaminopropionate (IR3535) Leads the Trend in Long-Lasting and Gentle Mosquito Repellents

As global health awareness continues to rise, consumers’ demands for mosquito repellent products have evolved beyond simply “keeping bugs away.” Today, they seek multi-dimensional benefits, including long-lasting protection, skin compatibility, and environmental friendliness. While traditional DEET is highly effective, its greasy feel, pungent odor, and tendency to damage plastics have deterred consumers pursuing a refined lifestyle. Against this backdrop, a green core ingredient known as Ethyl Butylacetylaminopropionate (commonly referred to as IR3535) is reshaping the personal care sector with its unique chemical structure and outstanding safety profile.

Safe,-Non-Toxic,-and-Universally-Applicable

I.What is Ethyl Butylacetylaminopropionate?

Ethyl Butylacetylaminopropionate is a colorless to pale yellow transparent liquid with a molecular weight of approximately 213.31 g/mol. As a β-alanine derivative, its chemical structure is meticulously designed, featuring butyl and ethyl groups connected by an amide bond. This specific molecular arrangement grants it excellent volatility control and balanced skin permeability. It not only provides continuous repellency for several hours but also boasts an extremely low skin penetration rate and an odorless profile, making it an ideal choice for infants, pregnant women, and individuals with sensitive skin. Currently endorsed and certified by authoritative bodies such as the World Health Organization (WHO), the U.S. Centers for Disease Control and Prevention (CDC), and the European CEB, it is widely recognized as a “new-generation green repellent.

II. Core Functions & Technical Advantages

1. Long-Lasting Broad-Spectrum Repellency

The Ethyl Butylacetylaminopropionate molecule effectively interferes with the olfactory receptors of mosquitoes, preventing them from locating human hosts and creating a physical-shield-like barrier. Clinical studies confirm that appropriately formulated Ethyl Butylacetylaminopropionate can provide up to 6–8 hours of protection, showing significant repellency against common blood-feeding insects like Aedes, Culex, and Anopheles mosquitoes. Its stable chemical properties ensure continuous release and sustained protection even in hot or humid outdoor environments.

2. Ultra-Gentle Skin Compatibility for a Refreshing Feel

Unlike traditional repellents that often cause stinging sensations or heavy greasiness, Ethyl Butylacetylaminopropionate has a pH level close to that of human skin and contains no harmful solvent residues. It offers robust protection without compromising the skin barrier or causing eye stinging or respiratory discomfort. Its refreshing texture allows users to breathe freely during hot summers, making it especially suitable for daily protection on the face and exposed body areas.

Long-Lasting-and-Gentle-Mosquito-Repellents

3. Eco-Friendly and Aligned with Sustainable Development

Ethyl Butylacetylaminopropionate exhibits excellent biodegradability, breaking down rapidly via microorganisms in natural water bodies and soil without causing persistent organic pollution. Its production adheres to green chemistry principles, avoiding high-risk raw materials like chlorine gas, thereby reducing the ecological footprint at the source. This makes it perfectly aligned with the stringent ESG (Environmental, Social, and Governance) standards currently required in the global cosmetics and daily chemical industries.

III. Application Scenarios & Market Potential

1. Personal Care & Outdoor Protection Products

Ethyl Butylacetylaminopropionate is a core ingredient for formulating various sprays, roll-ons, creams, and wipes. Whether it’s a portable spray for daily commutes or a long-lasting lotion for family trips, Ethyl Butylacetylaminopropionate delivers stable and efficient solutions. Its excellent formulation compatibility allows it to synergize with sunscreens, moisturizers, and plant essential oils, enabling the development of multifunctional products like “sunscreen + repellent” or “moisturizer + repellent” to meet one-stop care needs.

2. Textile Auxiliaries & Home Protection

Leveraging its good film-forming and wash-resistant properties, Ethyl Butylacetylaminopropionate is widely used in the post-finishing processes of functional textiles. Through microencapsulation technology, it can be embedded into fabric fibers to create mosquito-proof pants, camping tents, and baby sleeping bags, offering durable protection through dozens of washes. Additionally, in indoor air care, Ethyl Butylacetylaminopropionate is suitable for electric liquid vaporizers and aerosol formulas, providing an odorless and non-toxic indoor repellent experience.

3. Public Health & Medical Protection

Given its high safety grade, Ethyl Butylacetylaminopropionate demonstrates immense value in epidemic prevention, tropical disease control, and hospital perimeter management. As a key component in public area spraying agents, it helps block the source of mosquito-borne diseases like dengue fever and malaria. With minimal impact on non-target organisms in the environment, it serves as an ideal choice for building urban public health defense lines.

Ultra-Gentle-Skin-Compatibility-for-a-Refreshing-Feel

IV. Comprehensive Product Advantages

1.Safe, Non-Toxic, and Universally Applicable

Extensive toxicological tests have proven that Ethyl Butylacetylaminopropionate carries no risks of teratogenicity, carcinogenicity, or mutagenicity. It has extremely low oral toxicity and is non-irritating to eyes and skin. Explicitly approved for use in products for infants over six months old, it remains one of the few repellent ingredients on the market that combines high efficacy with ultimate safety.

2.Flexible Formulation & Strong Compatibility

Ethyl Butylacetylaminopropionate is highly compatible with various emulsion systems, sunscreen systems, and fragrance systems, minimizing the risk of chemical reactions that could cause efficacy loss. Its low viscosity and high fluidity facilitate automated filling and production, making it adaptable to water-based, oil-based, and alcohol-based carrier systems. This empowers brands to rapidly launch diverse end-products.

3.Reliable Stability & Mature Supply Chain

As a classic ingredient validated by decades of market use, Ethyl Butylacetylaminopropionate features mature and stable production processes, with raw material purity reaching over 99%. Standardized manufacturing ensures high consistency in color, odor, and active content across every batch, providing brand owners with solid quality assurance and efficient supply chain responsiveness.

Textile-Auxiliaries-&-Home-Protection

V. Conclusion

As consumers increasingly gravitate toward products that balance “invisible protection” with a “healthy lifestyle,” Ethyl Butylacetylaminopropionate is emerging as the core engine for next-generation mosquito repellents, thanks to its superior safety, long-lasting efficacy, and broad applicability. From urban commuting to wilderness exploration, from infant care to public health defense, Ethyl Butylacetylaminopropionate demonstrates remarkable adaptability across diverse scenarios and demographics.

We are committed to providing global customers with high-quality, high-purity Ethyl Butylacetylaminopropionate ingredients. Backed by advanced R&D support and a stable supply chain, we empower our partners to seize growth opportunities in the green repellent market. Industry peers are welcome to inquire about collaborations as we jointly open a new chapter in harmonious coexistence between humanity and nature.


Post time: Jul-22-2026