Tripeptide-29 CAS 2239-67-0
Tripeptide-29 for Cosmetic Manufacturing
Tripeptide-29 is a water-soluble, skin-conditioning peptide used in leave-on skincare. Also known as Gly-Pro-Hyp or H-Gly-Pro-Hyp-OH, it is an ingredient for facial serums, moisturising creams, lotions and peptide-focused eye care. Its collagen-related amino acid sequence makes it relevant to skincare ranges positioned around hydration, firmness and the appearance of fine lines.
Unilong serves cosmetic manufacturers, OEM/ODM producers and commercial ingredient distributors.
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Product Profile
| Item | Product information |
|---|---|
| INCI name | Tripeptide-29 |
| CAS number | 2239-67-0 |
| Chemical name | Glycyl-L-prolyl-4-hydroxy-L-proline |
| Peptide sequence | Gly-Pro-Hyp |
| Common synonym | H-Gly-Pro-Hyp-OH |
| Molecular formula | C12H19N3O5, unsalted peptide |
| Molecular weight | 285.30 g/mol, unsalted peptide |
| Solubility | Water soluble |
| Cosmetic function | Skin conditioning |
Tripeptide-29 in Leave-On Skincare
The Gly-Pro-Hyp sequence consists of glycine, proline and hydroxyproline, a three-residue motif found in collagen. Tripeptide-29 combines this defined molecular identity with water solubility for use in aqueous cosmetic systems. Its skin-conditioning role supports its selection as a peptide ingredient in daily facial care, including products with moisturising and fine-line care positioning.
The ingredient can be incorporated into aqueous serums and the water phase of emulsions. These formats extend from lightweight facial essences to richer moisturising creams. In each format, Tripeptide-29 provides the peptide component alongside the formula's humectants, emollients and texture ingredients.
Cosmetic Applications
Facial Serums and Essences
Tripeptide-29 is used in facial serums and essences featuring skin-conditioning peptides. Water-rich serum bases provide an aqueous medium for the ingredient. These formats suit skincare ranges focused on daily hydration, skin texture and the appearance of fine lines. The peptide forms part of the leave-on formulation alongside its other moisturising and skin-conditioning ingredients.
Face Creams and Lotions
Moisturising creams and lotions combine Tripeptide-29 with an emulsion-based skincare format. The water-soluble peptide is incorporated into the aqueous part of the formulation. Emollients and emulsifiers provide the cream or lotion texture, while Tripeptide-29 supplies its peptide component. Applications include daily facial moisturisers and morning or evening skincare ranges with firming and fine-line care positioning.
Facial Gels and Gel Serums
Aqueous facial gels and gel serums are potential formats for this hydrophilic peptide. These products offer a lighter texture within a leave-on skincare range. Tripeptide-29 is incorporated into the aqueous formulation, with the chosen gelling system providing structure and flow.
Eye Essences and Eye Creams
Tripeptide-29 is used in peptide-focused eye essences and eye creams. Its water solubility accommodates an aqueous essence or the aqueous portion of a cream. These formats fit cosmetic ranges positioned around moisturising care and the appearance of fine lines around the eyes.
Commercial Supply
Unilong's general shipment schedule is usually 7–15 days after order confirmation. The product-specific dispatch date depends on material availability, quantity and transport requirements. Packaging and MOQ form part of the agreed order terms.
Why Choose Unilong
Supplier qualification and order support for commercial Tripeptide-29 purchasing.
Factory Audit Coordination
For commercial purchasing projects, we can help coordinate factory audit requests with the relevant manufacturer. Site access, audit scope and scheduling depend on the manufacturer's agreement.
Product and Batch Documentation
Request the product specification or TDS, SDS and applicable batch COA for supplier approval. Source and composition declarations are based on the manufacturer's available records.
Independent Pre-shipment Inspection
Third-party inspection can be arranged before dispatch, including inspection by SGS where agreed. Inspection scope and acceptance requirements are specified for the order.
Shipment Approval and Delivery Coordination
Where pre-shipment approval is agreed, the goods are held until the buyer approves release. We also coordinate packing and shipping requirements for the order.
Procurement FAQ
Can I nominate an inspection agency?
You may nominate an independent agency for pre-shipment inspection. Access, scope and timing are agreed for the order.
Does the dispatch schedule include international transit?
No. The dispatch schedule covers shipment from the supplier. International transit time depends on the destination and transport route.
Can I obtain a batch COA?
A batch COA can be requested for the proposed material. Document availability is confirmed for the applicable batch.
Is a source declaration available?
Availability depends on the material and its supporting records. Include any mandatory source requirement with the order enquiry.
Ordering from Unilong
For commercial Tripeptide-29 orders, send the required specification, purchasing quantity and destination country. Add any mandatory packaging, document and delivery requirements. Contact Unilong to discuss supply for your cosmetic manufacturing programme.









