Madecassic acid with CAS 18449-41-7
Madecassic acid is a triterpenoid that has been found in C. asiatica and has diverse biological activities. It inhibits LPS-induced production of nitric oxide (NO), prostaglandin E2 (PGE2; Item No. 14010), TNF-α, IL-1β, and IL-6 in RAW 264.7 macrophages when used at a concentration of 150 μg/ml. Madecassic acid (0.05 and 0.1% in the diet) decreases plasma levels of fibrinogenin and triglycerides, as well as heart and kidney levels of reactive oxygen species (ROS), in a mouse model of diabetes induced by streptozotocin (STZ; Item No. 13104). It decreases tumor growth in a CT26 murine colon cancer model in a dose-dependent manner.
| CAS | 18449-41-7 |
| Names | Madecassic acid |
| Appearance | Powder |
| Purity | 98% |
| MF | C30H48O6 |
| Grade | Food $ Medical Grade |
| Package | 25kgs/bag,20tons/20’container |
| Brand Name | Unilong |
Madecassic Acid is a terpenoid with an ursane skeleton isolated from Centella asiatica. Madecassic Acid displays anti-inflammatory properties as a result of iNOS, COX-2, TNF-alpha, IL-1beta, and IL-6 inhibition via the downregulation of NF-kappaB activation in RAW 264.7 macrophage cells.
25kgs/drum,9tons/20'container
25kgs/bag,20tons/20'container
odium-dodecylbenzenesulphonate
