1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide Hydrochloride CAS 25952-53-8

CAS : 25952-53-8

Molecular formula: C8H18ClN3

EINECS: 247-361-2

Molecular weight: 191.7

Assay: 99%

Synonym: (3-dimethylaminopropyl)ethyl-carbodiimidmonohydrochloride; 3-propanediamine,n’-(ethylcarbonimidoyl)-n,n-dimethyl-monohydrochloride; 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydroc; AT test ,only COA; EDC.HCI; N'-(Ethylkohlenstoffimidoyl)-N,N-dimethylpropan-1,3-diaminmonohydrochlorid; Avanafil Impurity 40; Diquafosol Impurity m; carbodiimide HydrochL; oride (EDCI); 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride

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What is EDC HCl with CAS 25952-53-8?

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide Hydrochloride, abbreviated as EDC hydrochloride, molecular formula: C8H17N3·HCl, relative molecular weight is 191.70, white crystalline powder, easy moisture absorption, solubility in water >20g/100ml, soluble in ethanol, melting point 110-114℃, used as an activation reagent of carboxyl group in amide synthesis. It is also used in the preparation of activated phosphate groups, cross-linking of proteins and nucleic acids, and immunoconjugations.

Specification

Melting point	110-115 °C(lit.)
density	0.877 g/mL at 20 °C(lit.)
refractive index	n20/D 1.461
storage temp.	-20°C
solubility	H2O: soluble1 gm/10 ml, clear to very slightly hazy, colorless to very faintly yellow
form	Crystalline Powder
color	White to off-white

Application

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is being used for the synthesis of amides. EDC.HCl is also used as a coupling agent in the preparation of esters from carboxylic acids using dimethylaminopyridine as the catalyst. It is water-soluble carbodiimide, widely used for peptide coupling.