Top Suppliers 105-53-3 - SHIKONIN CAS 517-89-5 Shikonine – Unilong
Top Suppliers 105-53-3 - SHIKONIN CAS 517-89-5 Shikonine – Unilong Detail:
Purple-brown needle crystal, melting point 147℃, optical rotation αD20=+135°(benzene). Soluble in phenethyl ether, acetone, chloroform, methanol, ethanol, glycerol, animal and vegetable oils and alkaline aqueous solutions, insoluble in water. The hue changes with the Ph value, with a Ph value of 4-6 being red, a Ph value of 8 being purple, and a Ph value of 10-12 being blue. Good light resistance, heat resistance and oxidation resistance, unstable to reducing dose, and dark purple in case of iron ions. Has a certain antibacterial effect.
| CAS | 517-89-5 |
| Other Names | Shikonine |
| Appearance | purple powder |
| Purity | 99% |
| Color | purple |
| Storage | Cool Dried Storage |
| Package | 25kg/bag |
| Application | Food |
(1) Hypoglycemic effect The leaf extract of comfrey and the polysaccharide (A, B, C) of comfrey have obvious hypoglycemic effect.
(2) Bacteriostatic effect Lithospermum has an inhibitory effect on Jingke 68-1 virus in vitro, and has an inhibitory effect on Staphylococcus aureus. The anti-parainfluenza virus effect of levoshikonin was studied by hemagglutination reaction and cytopathic method. The results showed that it had low toxicity within the concentration range used in the experiment, and had certain in vitro anti-influenza virus activity and direct killing of parainfluenza virus. effect.
(3) Effects on blood coagulation: Intraperitoneal injection of shikonin components (shikonin, acetylshikonin) does not affect blood coagulation time, but can prevent the anticoagulant effect of heparin.
(4) Anti-tumor effect Comfrey extract has a certain inhibitory effect on the late stage (G2 phase) of DNA synthesis in Hela cells.
(5) Antitumor effect Shikonin inhibits proliferation, promotes apoptosis and induces cell cycle arrest in cultured human choriocarcinoma drug-resistant cell lines (JAR/MTX) in vitro. Experiments show that the concentration of shikonin increases with the dose. And the prolongation of the action time, the inhibition rate of the growth of choriocarcinoma drug-resistant cells also increased significantly.
(6) Effects on hormone secretion The effect of shikonin on the function of the hypothalamic-pituitary-gonadal axis in adolescent female rats showed that the serum hormone levels in the shikonin group were significantly lower than those in the negative control group, and there was no significant difference compared with the positive control group. different. It shows that shikonin can inhibit the function of hypothalamic-pituitary-gonadal axis in rats.
(7) Antioxidant effect Some researchers measured the scavenging ability of shikonin to superoxide radical (O2-) and 1,1-diphenyl-2-picrophenhydrazine radical (DPPH), and its effect on β- – Inhibition of the carotene/linoleic acid autoxidation system. The results showed that shikonin had strong scavenging ability to DPPH and O2-, and had obvious inhibitory effect on the auto-oxidation system of β-carotene/linoleic acid. Strong antioxidant capacity.
25kgs/drum,9tons/20’container
Product detail pictures:
Related Product Guide:
As a way to finest meet up with client's wants, all of our operations are strictly performed in line with our motto "High Quality, Aggressive Price, Fast Service" for Top Suppliers 105-53-3 - SHIKONIN CAS 517-89-5 Shikonine – Unilong , The product will supply to all over the world, such as: Serbia, French, Somalia, Our solutions have national accreditation requirements for qualified, good quality products, affordable value, was welcomed by individuals all over the world. Our products will continue to improve inside the order and appear forward to cooperation with you, Definitely should any of those goods be of curiosity to you, be sure to letus know. We'll be satisfied to supply you a quotation up on receipt of the detailed needs.
By Jill from Chile - 2018.12.22 12:52
We are long-term partners, there is no disappointment every time, we hope to maintain this friendship later!
By Sara from Botswana - 2017.10.23 10:29
