Poly(hexamethylenebiguanide)hydrochloride PHMB CAS 32289-58-0
The polyhamethylene biguanide hydrochloride corresponding to CAS 32289-58-0 (English name: Poly(hexamethylenebiguanide)hydrochloride, abbreviated as PHMB, is a cationic high-molecular polymer. Its core characteristics include highly efficient broad-spectrum antibacterial properties, low toxicity, low irritation, strong stability, and low susceptibility to drug resistance. Polyhexamethylene biguanide is currently a widely used new type of bactericide/preservative. Play a core role in multiple fields
The average molecular weight of polyhexamethylene biguanidine hydrochloride is 1100~1800, CAS 32289-58-0 and the molecular formula is (C8H17N5) n · xHCl, n=12-16. Polyhexamethylene biguanidine hydrochloride (PHMB) is a broad-spectrum antibiotic that can kill gram-positive bacteria, gram-negative bacteria, fungi and yeast.
| Item | Specifications | Specifications | Specifications |
| Appearance | White powder | colorless translucent crystals | colorless liquid |
| Purity | 95%; 98% | ≥98% | 20%;25%;50% |
| Density(20℃) | 1.039~1.046g/cm3 | 1.039~1.046g/cm3 | 1.039~1.046g/cm3 |
| PH value(20℃) | 4.0~6.0 | 4.0~6.0 | 4.0~6.0 |
| Absorbance(237nm) | ≥400 | ≥400 | ≥400 |
| Absorbance(237nm/222nm) | 1.2~1.6 | 1.2~1.6 | 1.2~1.6 |
This bactericide is a broad-spectrum antibacterial agent with killing ability against gram-positive bacteria, gram-negative bacteria, fungi and yeast; Polyhexamethylene biguanide can be used as a fungicide and is often used as a disinfectant for swimming pools, universal cleaners and disinfectants.
High-frequency field: Daily chemicals and cosmetics field
Cosmetic preservative: PHMB CAS 32289-58-0 is used in products such as toner, lotion, face cream, mask, shampoo and conditioner to inhibit the growth of bacteria (such as Staphylococcus aureus) and fungi (mold, yeast), and prevent product deterioration. It has strong compatibility (does not conflict with most cosmetic ingredients), no odor, and does not affect the skin feel of the product (the maximum allowable concentration in cosmetics is usually 0.3%).
Antibacterial ingredients in personal care products: PHMB CAS 32289-58-0 is used in antibacterial hand sanitizers, body washes, oral care products (toothpaste, mouthwash), feminine care lotions, etc. PHMB reduces harmful microorganisms on the skin, mouth and private parts through its bactericidal effect, prevents bad breath and inflammation (such as athlete's foot, bad breath and itchy private parts), and is gentle without damaging the skin/mucous membrane barrier.
✅Broad-spectrum antibacterial effect: Polyhexamethylene biguanide has inhibitory effects on Gram-positive bacteria, Gram-negative bacteria, fungi, and viruses (some enveloped viruses).
✅The mechanism of action is unique: electrostatic adsorption destroys cell membranes and is less likely to cause drug resistance.
✅Safe and gentle: Low toxicity, low irritation, no residue, meeting environmental protection and safety standards;
✅Strong stability: Adaptable to various pH ranges and processing conditions, and easy to use.
Powder
25kgs/drum, 9tons/20’container
25kgs/bag, 20tons/20’container
Liquid
200kgs/drum, 16tons/20’container
250kgs/drum,20tons/20’container
1250kgs/IBC, 20tons/20’container
Polyhexamethylene biguanide PHMB CAS 32289-58-0
Polyhexamethylene biguanide PHMB CAS 32289-58-0












