OEM/ODM Factory Cosmetic Material - Madecassic acid with CAS 18449-41-7 – Unilong

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OEM/ODM Factory Cosmetic Material - Madecassic acid with CAS 18449-41-7 – Unilong Detail:

Madecassic acid is a triterpenoid that has been found in C. asiatica and has diverse biological activities. It inhibits LPS-induced production of nitric oxide (NO), prostaglandin E2 (PGE2; Item No. 14010), TNF-α, IL-1β, and IL-6 in RAW 264.7 macrophages when used at a concentration of 150 μg/ml. Madecassic acid (0.05 and 0.1% in the diet) decreases plasma levels of fibrinogenin and triglycerides, as well as heart and kidney levels of reactive oxygen species (ROS), in a mouse model of diabetes induced by streptozotocin (STZ; Item No. 13104). It decreases tumor growth in a CT26 murine colon cancer model in a dose-dependent manner.

CAS	18449-41-7
Names	Madecassic acid
Appearance	Powder
Purity	98%
MF	C30H48O6
Grade	Food $ Medical Grade
Package	25kgs/bag,20tons/20’container
Brand Name	Unilong

Madecassic Acid is a terpenoid with an ursane skeleton isolated from Centella asiatica. Madecassic Acid displays anti-inflammatory properties as a result of iNOS, COX-2, TNF-alpha, IL-1beta, and IL-6 inhibition via the downregulation of NF-kappaB activation in RAW 264.7 macrophage cells.

25kgs/drum,9tons/20′container

25kgs/bag,20tons/20′container

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