Ethyl nicotinate CAS 614-18-6
Ethyl nicotinate, chemically known as ethyl pyridine-3-formate, is an ester derivative of niacin (vitamin B3). It is a colorless to pale yellow transparent liquid with a slight, distinctive fruity aroma. In the commercial and industrial fields, ethyl nicotinate is also known as ethyl paraben or ethyl nicotinate. Ethyl nicotinate is insoluble in water but miscible with organic solvents such as ethanol, ether and chloroform.
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ITEM |
STANDARD |
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Properties |
colorless or light yellow transparent liquid |
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Content |
99.80% |
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Water |
0.10% |
1. Medical field: Focus on "vitamin supplementation" and "local treatment"
As a pharmaceutical intermediate or direct medicinal component, the core value of ethyl niacin lies in its "mild supplementation of vitamin B3" and "local targeting effect".
2. Daily chemical industry: Focusing on "skin care" and "hair health"
With its "mild activity + good permeability", ethyl niacin is often used in "functional formulas" in skin care and hair care products:
3. Food and Feed Field: "Nutritional Fortification" and "Flavor Improvement"
Food nutrient fortifier
Vitamin B3 fortification for baked goods (such as bread and biscuits), sports drinks, and complementary foods for infants and young children usually has an addition rate of 0.01% to 0.05% (based on the total amount of food). For instance, adding ethyl nicotinate to infant rice cereal can prevent the sourness of niacin from affecting the taste, while meeting the infant's need for vitamin B3 (the recommended daily intake is approximately 4mg).
4. Other fields: Industrial and scientific research applications
Organic synthesis intermediates: They are used in the synthesis of pyridine derivatives (such as pharmaceutical intermediates and dyes), and the ethyl ester group can act as a "removable protecting group", introducing other functional groups through hydrolysis or reduction reactions.
Flavoring auxiliary components: A small amount (0.001%-0.005%) added to tobacco flavoring can improve the mellow taste of tobacco and mask pungent odors.
Research reagent: Used in biochemical experiments as a probe molecule for "niacin metabolism research", ethyl nicotinate tracks the transformation pathway of niacin within cells.
1. Ethyl nicotinate is mild, low-irritating and has a low risk of flushing. Ethyl nicotinate is superior to niacin and is suitable for sensitive skin, as well as for oral sensitive skin care products and oral vitamin supplements.
2. Ethyl nicotinate has a high bioavailability and can easily penetrate the skin and mucous membranes. After being hydrolyzed into niacin, it has high activity and its functional efficiency is superior to that of niacin external blood-activating gel and hair care and anti-hair loss products.
3. Ethyl nicotinate is compatible and easily soluble in oil/water systems, and has no conflict with surfactants, preservatives, vitamins and other ingredients. Ethyl nicotinate is a compound skin care product and food fortification formula.
4. Ethyl nicotinate is safe for oral and topical use with low toxicity and has passed safety certifications in multiple countries. Ethyl nicotinate is suitable for a wide range of people (infants and the elderly), including infant food and pharmaceutical preparations.
25kgs/drum, 9tons/20’container
25kgs/bag, 20tons/20’container
Ethyl nicotinate CAS 614-18-6
Ethyl nicotinate CAS 614-18-6












