Betadex Sulfobutyl Ether Sodium CAS 182410-00-0

CAS: 182410-00-0

Purity: 100.2%

Molecular Formula: C70H119Na7O56S7

Molecular Weight: 2242.05

Synonyms: sulfobutyl ethers; SBE-β-CD(Sulfobutyl Ether-β-cyclodextrin Sodium salt); sulfobutyl ether sodium salt; betadex sulfobuytl ether sodium; β-Cyclodextrin, sulfobutyl ethers; Sulfobutylated beta-cyclodextrin sodium salt (DS~4); Sulfobutyl beta cyclodextrin; Sulphobutylether β-cyclodextrin sodium;sulfobutyl ether B-cyclodextrin

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What is Betadex Sulfobutyl Ether Sodium CAS 182410-00-0?

Sodium sulfobutyl cyclodextrin is a highly water-soluble and safe cyclodextrin derivative obtained through chemical modification. Betadex sulfobutyl ether sodium is like a "universal solvent" that can wrap drugs that are insoluble in water and "carry" them to dissolve in water. Betadex sulfobutyl ether sodium is widely used in various dosage forms of drugs and is the "star excipient" of modern pharmaceutical industry.

Specification

Appearance	White crystalline powder
Assay	95.0%-105.0%
Heavy Metals	≤5
Sodium Chloride	≤0.2
Bate Cyclodextrin	≤0.1
Bacterial Endotoxins	≤0.02

Application

Sodium sulfobutyl ether - β - cyclodextrin is a novel excipient for pharmaceutical formulations, belonging to a sulfonic acid derivative of anionic highly water-soluble cyclodextrin. Betadex sulfobutyl ether sodium can form non covalent complexes with drug molecules well, improving the stability, water solubility, safety, and effectively enhancing the biological activity of drug molecules. Its low nephrotoxicity can alleviate drug hemolysis and control drug release rate.

Features

✅Extremely high water solubility: Betadex sulfobutyl ether sodium is solubility in water far exceeds that of the parent β - cyclodextrin (>70g/100mL), making it easy to prepare high concentration solutions.

✅Low surface activity: Betadex sulfobutyl ether sodium does not have the inherent irritant properties of surfactants, and has little destructive effect on cell membranes, further improving its medication safety.

✅Stability: Its chemical properties are stable, not easily degraded, and can maintain long-lasting effects under conventional formulation processes and storage conditions, ensuring the quality and shelf life of the drug.