1,3,6,8-PYRENETETRASULFONIC ACID TETRASODIUM SALT CAS 59572-10-0
1,3,6,8-Pyrenetetrasulfonic acid tetrasodium salt (commonly referred to as Pyranine or HPTS) is a very important fluorescent dye and chemical intermediate. Its molecular structure is based on pyrene (a polycyclic aromatic hydrocarbon) and is connected to four sulfonic acid groups (-SO₃Na), which gives it unique properties.
|
Appearance |
Light Yellow Powder |
|
Content |
≥98% |
|
Insolubles |
≤0.1% |
|
PH |
4.5-8.5 |
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Moisture |
≤0.5% |
1. Fluorescent Probes and Sensors:
pH Sensors: This is its most classic and important application. Its fluorescence intensity is highly sensitive to the pH of the environment. Fluorescence is weak under acidic conditions, but very strong under alkaline conditions (pH ~7-9). Therefore, it is widely used in the preparation of fluorescent pH test strips, intracellular pH imaging, and microenvironmental pH monitoring.
Ion Detection: Its fluorescence is also quenched by certain metal ions (such as Fe₃⁺ and Cu₂⁺), making it useful for detecting the presence of these ions.
Biomolecule Research: 1,3,6,8-Pyrenetetrasulfonic acid tetrasodium salt is used to study the structure and dynamics of biomacromolecules such as proteins and DNA, detecting changes in the microenvironment surrounding biomolecules through fluorescence changes.
2. Biological Staining and Labeling:
Due to its excellent water solubility and cell membrane permeability, it can be used for staining live cells, specifically for visualizing the internal pH environment of organelles like lysosomes (acidic environment) or the cytoplasm (neutral environment).
3. Photophysical and Photochemical Research:
1,3,6,8-Pyrenetetrasulfonic acid tetrasodium salt can be used as an energy donor in fluorescence energy transfer (FRET) due to its high fluorescence quantum yield and suitable excitation/emission spectrum.
1,3,6,8-Pyrenetetrasulfonic acid tetrasodium salt can be used to study photochemical processes such as proton transfer and electron transfer.
4. Industrial Applications:
Fluorescent Brightener: 1,3,6,8-Pyrenetetrasulfonic acid tetrasodium saltcan be used to whiten high-quality paper and textiles.
Photocuring Initiator: 1,3,6,8-Pyrenetetrasulfonic acid tetrasodium salt can be used as a photosensitizer or co-initiator in certain UV-curing systems.
Water Treatment Tracer: Due to its water solubility and strong fluorescence, 1,3,6,8-Pyrenetetrasulfonic acid tetrasodium salt can be used to detect leaks in water systems or study fluid dynamics.
5. Chemical Synthesis Intermediate:
The sulfonic acid group on its molecule can serve as a reaction site for the synthesis of more.
✅High sensitivity and accuracy
✅Relatively good biocompatibility and high cost-effectiveness
✅As a mature commercial product, its production costs are relatively manageable and readily available
25kgs/drum, 9tons/20’container
25kgs/bag, 20tons/20’container
1,3,6,8-PYRENETETRASULFONIC ACID TETRASODIUM SALT CAS 59572-10-0
1,3,6,8-PYRENETETRASULFONIC ACID TETRASODIUM SALT CAS 59572-10-0
